TYPO3 Core

same for /typo3/index.php?route=%2Fajax%2Fcontext-menu&token=2eb215ab8a434a5d1b473425f2cf08fbe4efc8d9&table=pages&uid=10&

might be related to #90104

Which mysql server version are you using?
What driver is used in TYPO3_CONF_VARS/DB/Connections/Default/driver?

TYPO3-Version
10.3.0
Webserver
Apache
PHP-Version
7.2.10
Datenbank (Default)
MySQL 5.5.62
Anwendungskontext
Production
Composer-Modus
Aktiviert
Betriebssystem
Linux 4.19.44-gentoo-mw1
Letzter Lauf des Planer
25-02-20 um 22:19, Dauer 0 Min, (gestartet automatisch)

charset = utf8mb4
    dbname = **
    driver = mysqli
    host = **
    password = **
    port = **
    tableoptions
        charset = utf8mb4
        collate = utf8mb4_unicode_ci
    user = **

I have the same error

Markus Klein wrote:

Which mysql server version are you using?

MariaDB 10.3.21 database server

What driver is used in TYPO3_CONF_VARS/DB/Connections/Default/driver?

mysqli

(1/1) Doctrine\DBAL\Driver\Mysqli\MysqliException

in /var/www/html/typo3_src-10.3.0/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/Mysqli/MysqliStatement.php line 237

            $values[$parameter] = $value;
        }

        if (! $this->_stmt->bind_param($types, ...$values)) {
            throw new MysqliException($this->_stmt->error, $this->_stmt->sqlstate, $this->_stmt->errno);
        }

        $this->sendLongData($streams);
    }

at Doctrine\DBAL\Driver\Mysqli\MysqliStatement->bindTypedParameters()
in /var/www/html/typo3_src-10.3.0/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/Mysqli/MysqliStatement.php line 146

                if (! $this->bindUntypedValues($params)) {
                    throw new MysqliException($this->_stmt->error, $this->_stmt->errno);
                }
            } else {
                $this->bindTypedParameters();
            }
        }

        if (! $this->_stmt->execute()) {

at Doctrine\DBAL\Driver\Mysqli\MysqliStatement->execute()
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Utility/BackendUtility.php line 461

                $statement = $queryBuilder->execute();
                $runtimeCache->set('getPageForRootlineStatement-' . $statementCacheIdent, $statement);
            } else {
                $statement->bindValue(1, (int)$uid);
                $statement->execute();
            }
            $row = $statement->fetch();
            $statement->closeCursor();

at TYPO3\CMS\Backend\Utility\BackendUtility::getPageForRootline(1, '', false, array())
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Utility/BackendUtility.php line 350

            $loopCheck = 100;
            $theRowArray = [];
            while ($uid != 0 && $loopCheck) {
                $loopCheck--;
                $row = self::getPageForRootline($uid, $clause, $workspaceOL, $additionalFields);
                if (is_array($row)) {
                    $uid = $row['pid'];
                    $theRowArray[] = $row;
                } else {

at TYPO3\CMS\Backend\Utility\BackendUtility::BEgetRootLine(1)
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/SiteResolver.php line 62

        if (MathUtility::canBeInterpretedAsInteger($pageId)) {
            $pageId = (int)$pageId;
            $rootLine = null;
            if ($pageId > 0) {
                $rootLine = BackendUtility::BEgetRootLine($pageId);
            }
            $site = $this->siteMatcher->matchByPageId($pageId, $rootLine);
            $request = $request->withAttribute('site', $site);
        }

at TYPO3\CMS\Backend\Middleware\SiteResolver->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/AdditionalResponseHeaders.php line 39

     * @return ResponseInterface
     */
    public function process(ServerRequestInterface $request, RequestHandlerInterface $handler): ResponseInterface
    {
        $response = $handler->handle($request);
        foreach ($GLOBALS['TYPO3_CONF_VARS']['BE']['HTTP']['Response']['Headers'] ?? [] as $header) {
            [$headerName, $value] = explode(':', $header, 2);
            $response = $response->withAddedHeader($headerName, trim($value));
        }

at TYPO3\CMS\Backend\Middleware\AdditionalResponseHeaders->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/OutputCompression.php line 45

        ob_clean();
        // Initialize output compression if configured
        $this->initializeOutputCompression();

        return $handler->handle($request);
    }

    /**
     * Initialize output compression if configured

at TYPO3\CMS\Backend\Middleware\OutputCompression->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/BackendUserAuthenticator.php line 71

        // @todo: once this logic is in this method, the redirect URL should be handled as response here
        $GLOBALS['BE_USER']->backendCheckLogin($this->isLoggedInBackendUserRequired($pathToRoute));
        $GLOBALS['LANG'] = LanguageService::createFromUserPreferences($GLOBALS['BE_USER']);

        $response = $handler->handle($request);

        // Additional headers to never cache any PHP request should be sent at any time when
        // accessing the TYPO3 Backend
        return $this->applyHeadersToResponse($response);

at TYPO3\CMS\Backend\Middleware\BackendUserAuthenticator->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/BackendRouteInitialization.php line 55

        // Add the route path to the request
        $request = $request->withAttribute('routePath', $pathToRoute);

        return $handler->handle($request);
    }
}

at TYPO3\CMS\Backend\Middleware\BackendRouteInitialization->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/ForcedHttpsBackendRedirector.php line 53

            [$server, $address] = explode('/', $url, 2);
            return new RedirectResponse('https://' . $server . $sslPortSuffix . '/' . $address);
        }

        return $handler->handle($request);
    }
}

at TYPO3\CMS\Backend\Middleware\ForcedHttpsBackendRedirector->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/LockedBackendGuard.php line 71

            $request->getAttribute('normalizedParams')->getRemoteAddress(),
            trim((string)$GLOBALS['TYPO3_CONF_VARS']['BE']['IPmaskList'])
        );

        return $handler->handle($request);
    }

    /**
     * Check adminOnly configuration variable and redirects to an URL in file typo3conf/LOCK_BACKEND

at TYPO3\CMS\Backend\Middleware\LockedBackendGuard->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Middleware/NormalizedParamsAttribute.php line 43

     */
    public function process(ServerRequestInterface $request, RequestHandlerInterface $handler): ResponseInterface
    {
        $request = $request->withAttribute('normalizedParams', NormalizedParams::createFromRequest($request));
        return $handler->handle($request);
    }
}

at TYPO3\CMS\Core\Middleware\NormalizedParamsAttribute->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 76

     * @return ResponseInterface
     */
    public function handle(ServerRequestInterface $request): ResponseInterface
    {
        return $this->tip->handle($request);
    }

    /**
     * Seed the middleware stack with the inner request handler

at TYPO3\CMS\Core\Http\MiddlewareDispatcher->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/AbstractApplication.php line 83

     * @return ResponseInterface
     */
    protected function handle(ServerRequestInterface $request): ResponseInterface
    {
        return $this->requestHandler->handle($request);
    }

    /**
     * Set up the application and shut it down afterwards

at TYPO3\CMS\Core\Http\AbstractApplication->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Http/Application.php line 61

            return $this->installToolRedirect();
        }
        // Set up the initial context
        $this->initializeContext();
        return parent::handle($request);
    }

    /**
     * Check if LocalConfiguration.php and PackageStates.php exist

at TYPO3\CMS\Backend\Http\Application->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/AbstractApplication.php line 95

    final public function run(callable $execute = null)
    {
        try {
            $response = $this->handle(
                \TYPO3\CMS\Core\Http\ServerRequestFactory::fromGlobals()
            );
            if ($execute !== null) {
                call_user_func($execute);
            }

at TYPO3\CMS\Core\Http\AbstractApplication->run()
in /var/www/html/typo3_src-10.3.0/typo3/index.php line 24

// Set up the application for the backend
call_user_func(function () {
    $classLoader = require dirname(__DIR__).'/vendor/autoload.php';
    \TYPO3\CMS\Core\Core\SystemEnvironmentBuilder::run(1, \TYPO3\CMS\Core\Core\SystemEnvironmentBuilder::REQUESTTYPE_BE);
    \TYPO3\CMS\Core\Core\Bootstrap::init($classLoader)->get(\TYPO3\CMS\Backend\Http\Application::class)->run();
});

at {closure}()
in /var/www/html/typo3_src-10.3.0/typo3/index.php line 25

call_user_func(function () {
    $classLoader = require dirname(__DIR__).'/vendor/autoload.php';
    \TYPO3\CMS\Core\Core\SystemEnvironmentBuilder::run(1, \TYPO3\CMS\Core\Core\SystemEnvironmentBuilder::REQUESTTYPE_BE);
    \TYPO3\CMS\Core\Core\Bootstrap::init($classLoader)->get(\TYPO3\CMS\Backend\Http\Application::class)->run();
});

It looks like the PHP's prepared statement is lost on the database-side for some reason.
So PHP tries to re-use the prepared statement, but the database has no clue about it anymore.
Could you please try, if you have the same issue, if you use the PDO driver instead?

(1/1) PDOException

You cannot serialize or unserialize PDOStatement instances
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Cache/Frontend/VariableFrontend.php line 59

            ];
            GeneralUtility::callUserFunction($_funcRef, $params, $this);
        }
        if (!$this->backend instanceof TransientBackendInterface) {
            $variable = serialize($variable);
        }
        $this->backend->set($entryIdentifier, $variable, $tags, $lifetime);
    }

at PDOStatement->__sleep()
at serialize(object(TYPO3\CMS\Core\Database\Driver\PDOStatement))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Cache/Frontend/VariableFrontend.php line 59

            ];
            GeneralUtility::callUserFunction($_funcRef, $params, $this);
        }
        if (!$this->backend instanceof TransientBackendInterface) {
            $variable = serialize($variable);
        }
        $this->backend->set($entryIdentifier, $variable, $tags, $lifetime);
    }

at TYPO3\CMS\Core\Cache\Frontend\VariableFrontend->set('getPageForRootlineStatement-d41d8cd98f00b204e9800998ecf8427e', object(TYPO3\CMS\Core\Database\Driver\PDOStatement))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Utility/BackendUtility.php line 458

                        $queryBuilder->expr()->eq('uid', $queryBuilder->createPositionalParameter($uid, \PDO::PARAM_INT)),
                        QueryHelper::stripLogicalOperatorPrefix($clause)
                    );
                $statement = $queryBuilder->execute();
                $runtimeCache->set('getPageForRootlineStatement-' . $statementCacheIdent, $statement);
            } else {
                $statement->bindValue(1, (int)$uid);
                $statement->execute();
            }

at TYPO3\CMS\Backend\Utility\BackendUtility::getPageForRootline(1, '', false, array())
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Utility/BackendUtility.php line 350

            $loopCheck = 100;
            $theRowArray = [];
            while ($uid != 0 && $loopCheck) {
                $loopCheck--;
                $row = self::getPageForRootline($uid, $clause, $workspaceOL, $additionalFields);
                if (is_array($row)) {
                    $uid = $row['pid'];
                    $theRowArray[] = $row;
                } else {

at TYPO3\CMS\Backend\Utility\BackendUtility::BEgetRootLine(1)
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/SiteResolver.php line 62

        if (MathUtility::canBeInterpretedAsInteger($pageId)) {
            $pageId = (int)$pageId;
            $rootLine = null;
            if ($pageId > 0) {
                $rootLine = BackendUtility::BEgetRootLine($pageId);
            }
            $site = $this->siteMatcher->matchByPageId($pageId, $rootLine);
            $request = $request->withAttribute('site', $site);
        }

at TYPO3\CMS\Backend\Middleware\SiteResolver->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/AdditionalResponseHeaders.php line 39

     * @return ResponseInterface
     */
    public function process(ServerRequestInterface $request, RequestHandlerInterface $handler): ResponseInterface
    {
        $response = $handler->handle($request);
        foreach ($GLOBALS['TYPO3_CONF_VARS']['BE']['HTTP']['Response']['Headers'] ?? [] as $header) {
            [$headerName, $value] = explode(':', $header, 2);
            $response = $response->withAddedHeader($headerName, trim($value));
        }

at TYPO3\CMS\Backend\Middleware\AdditionalResponseHeaders->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/OutputCompression.php line 45

        ob_clean();
        // Initialize output compression if configured
        $this->initializeOutputCompression();

        return $handler->handle($request);
    }

    /**
     * Initialize output compression if configured

at TYPO3\CMS\Backend\Middleware\OutputCompression->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/BackendUserAuthenticator.php line 71

        // @todo: once this logic is in this method, the redirect URL should be handled as response here
        $GLOBALS['BE_USER']->backendCheckLogin($this->isLoggedInBackendUserRequired($pathToRoute));
        $GLOBALS['LANG'] = LanguageService::createFromUserPreferences($GLOBALS['BE_USER']);

        $response = $handler->handle($request);

        // Additional headers to never cache any PHP request should be sent at any time when
        // accessing the TYPO3 Backend
        return $this->applyHeadersToResponse($response);

at TYPO3\CMS\Backend\Middleware\BackendUserAuthenticator->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/BackendRouteInitialization.php line 55

        // Add the route path to the request
        $request = $request->withAttribute('routePath', $pathToRoute);

        return $handler->handle($request);
    }
}

at TYPO3\CMS\Backend\Middleware\BackendRouteInitialization->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/ForcedHttpsBackendRedirector.php line 53

            [$server, $address] = explode('/', $url, 2);
            return new RedirectResponse('https://' . $server . $sslPortSuffix . '/' . $address);
        }

        return $handler->handle($request);
    }
}

at TYPO3\CMS\Backend\Middleware\ForcedHttpsBackendRedirector->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Middleware/LockedBackendGuard.php line 71

            $request->getAttribute('normalizedParams')->getRemoteAddress(),
            trim((string)$GLOBALS['TYPO3_CONF_VARS']['BE']['IPmaskList'])
        );

        return $handler->handle($request);
    }

    /**
     * Check adminOnly configuration variable and redirects to an URL in file typo3conf/LOCK_BACKEND

at TYPO3\CMS\Backend\Middleware\LockedBackendGuard->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Middleware/NormalizedParamsAttribute.php line 43

     */
    public function process(ServerRequestInterface $request, RequestHandlerInterface $handler): ResponseInterface
    {
        $request = $request->withAttribute('normalizedParams', NormalizedParams::createFromRequest($request));
        return $handler->handle($request);
    }
}

at TYPO3\CMS\Core\Middleware\NormalizedParamsAttribute->process(object(TYPO3\CMS\Core\Http\ServerRequest), object(class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 153

                if (!$middleware instanceof MiddlewareInterface) {
                    throw new \InvalidArgumentException(get_class($middleware) . ' does not implement ' . MiddlewareInterface::class, 1516821342);
                }
                return $middleware->process($request, $this->next);
            }
        };
    }
}

at class@anonymous/var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php0x7f498ed632b2->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/MiddlewareDispatcher.php line 76

     * @return ResponseInterface
     */
    public function handle(ServerRequestInterface $request): ResponseInterface
    {
        return $this->tip->handle($request);
    }

    /**
     * Seed the middleware stack with the inner request handler

at TYPO3\CMS\Core\Http\MiddlewareDispatcher->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/AbstractApplication.php line 83

     * @return ResponseInterface
     */
    protected function handle(ServerRequestInterface $request): ResponseInterface
    {
        return $this->requestHandler->handle($request);
    }

    /**
     * Set up the application and shut it down afterwards

at TYPO3\CMS\Core\Http\AbstractApplication->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/backend/Classes/Http/Application.php line 61

            return $this->installToolRedirect();
        }
        // Set up the initial context
        $this->initializeContext();
        return parent::handle($request);
    }

    /**
     * Check if LocalConfiguration.php and PackageStates.php exist

at TYPO3\CMS\Backend\Http\Application->handle(object(TYPO3\CMS\Core\Http\ServerRequest))
in /var/www/html/typo3_src-10.3.0/typo3/sysext/core/Classes/Http/AbstractApplication.php line 95

    final public function run(callable $execute = null)
    {
        try {
            $response = $this->handle(
                \TYPO3\CMS\Core\Http\ServerRequestFactory::fromGlobals()
            );
            if ($execute !== null) {
                call_user_func($execute);
            }

at TYPO3\CMS\Core\Http\AbstractApplication->run()
in /var/www/html/typo3_src-10.3.0/typo3/index.php line 24

// Set up the application for the backend
call_user_func(function () {
    $classLoader = require dirname(__DIR__).'/vendor/autoload.php';
    \TYPO3\CMS\Core\Core\SystemEnvironmentBuilder::run(1, \TYPO3\CMS\Core\Core\SystemEnvironmentBuilder::REQUESTTYPE_BE);
    \TYPO3\CMS\Core\Core\Bootstrap::init($classLoader)->get(\TYPO3\CMS\Backend\Http\Application::class)->run();
});

at {closure}()
in /var/www/html/typo3_src-10.3.0/typo3/index.php line 25

call_user_func(function () {
    $classLoader = require dirname(__DIR__).'/vendor/autoload.php';
    \TYPO3\CMS\Core\Core\SystemEnvironmentBuilder::run(1, \TYPO3\CMS\Core\Core\SystemEnvironmentBuilder::REQUESTTYPE_BE);
    \TYPO3\CMS\Core\Core\Bootstrap::init($classLoader)->get(\TYPO3\CMS\Backend\Http\Application::class)->run();
});

Could you please check your cache configuration for the cache "runtime"?
It MUST use 'backend' => \TYPO3\CMS\Core\Cache\Backend\TransientMemoryBackend::class or any backend extending TransientBackendInterface. Obviously it does not in your case.
Consequently it tries to serialize the statement, which fails in case of PDO. Maybe this is also the cause for the error with the mysqli driver.

After changing the cache configuration, everything works with the driver "mysqli" and "pdo_mysql".
Thank you very much!

for me too, thx

i think it would be good to throw an error if any wrong cache has been chosen