TYPO3 Core

1. Setup TypoScript rendering

   page >
   page = PAGE
   page.10 = TEXT
   page.10.value = test
   

2. Log in to the TYPO3 backend
3. Load a frontend page
4. Change TypoScript, e.g.

   page.10.value = test new

5. re load frontend page without cache, e.g. by pressing CTRL+SHIFT+r on Linux

This should load the frontend without caches which worked fine in 11.5 and older versions.
But this does no longer work in current main, the TypoScript seems to be loaded from cache.
Adjusting TypoScript setup inside the filesystem only takes effect after clearing the cache e.g. via install tool, Maintenance Module, "Flush frontend cache", "Flush all caches".